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Monitor Closely (2)pentobarbital will lower the level or impact of suvorexant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Potent CYP3A4 inducers may lessen suvorexant efficacy; if amplified suvorexant dose needed, don't exceed twenty mg/working daypentobarbital will lower the level or influence of eletriptan by affe